At Notre Dame, fighting cancer is not confined to one discipline. It’s the work of engineers, chemists, biologists, industrial designers, and more.
Cancer Research
Cancer Research
News
Notre Dame researchers have created a tiny, wireless LED implant that uses green light to destroy deep-seated tumors. By triggering a specific type of cell death called pyroptosis, this device not only kills cancer cells but also prompts the immune system to join the fight.
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To invade healthy tissues and continue growing, aggressive cancers mimic and circumvent the body’s native piping system of veins and arteries. Through this process, known as vasculogenic mimicry (VM), tumor cells form fluid-conducting channels that transport blood, oxygen, and nutrients directly to the growing tumor. This behavior enables tumor metastasis...
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Organic chemistry has numerous applications in the real world, especially in the realm of medicinal chemistry. Due to the complexity within organic chemistry, there is a great potential for developing molecules with several applications. When he was a child, Pratik Yadav, assistant research professor in the Department of Chemistry and...
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To think, feel, talk and move, neurons send messages through electrical signals in the brain and spinal cord. This intricate communication network is built of billions of neurons connected by synapses and managed and modified by glial cells. When neurons die, this communication network is disrupted and since this loss...
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In the quiet spaces of pediatric oncology, Dr. Christy Lucas ’16 finds purpose in being a faithful narrator — helping patients and families tell, to the very last pages, the stories they never thought they’d have to write. Lucas’ dedication to service may have begun as a Miracle League volunteer...
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Today, the University of Notre Dame and Beacon Health System announced a new, multiyear research collaboration. Through this agreement, Notre Dame and Beacon will jointly develop collaborative, health-focused research projects that are of interest to both organizations, particularly in the areas of oncology and health data. Within these projects, Notre...
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Any student who has studied abroad will tell you that stepping outside your comfort zone is a necessary part of the process—and worth it. But many of them do so in the company of other students, often even friends, who are in the same program. When Jennifer Leon '27 decided...
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While the incidence of breast cancer is highest for white women, Black women are more likely to have early-onset or more aggressive subtypes of breast cancer, such as triple-negative breast cancer. Among women under 50, the disparity is even greater: young Black women have double the mortality rate of young...
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Researchers at the University of Notre Dame have developed a novel, automated device capable of diagnosing glioblastoma, a fast-growing and incurable brain cancer, in less than an hour. The average glioblastoma patient survives 12-18 months after diagnosis. The crux of the diagnostic is a biochip that uses electrokinetic technology to...
News
Serious quality defects were found in a significant number of cancer medications from sub-Saharan Africa, according to new research from the University of Notre Dame. For the study published in The Lancet Global Health, researchers collected different cancer medications from Cameroon, Ethiopia, Kenya and Malawi and evaluated whether each drug...
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Xin Lu Adding a pre-ketone supplement — a component of a high-fat, low-carb ketogenic diet — to a type of cancer therapy in a laboratory setting was highly effective for treating prostate cancer, researchers from the University of Notre Dame found. Recently published online in the journal Cancer Research, the study...
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What could cancer teach us about tuberculosis? That’s a question Meenal Datta has been chasing since she was a graduate student. Once the body’s immune system is infected with tuberculosis, it forms granulomas — tight clusters of white blood cells — in an attempt to wall off the infection-causing bacteria...
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A new study links a high body mass index (BMI) to alterations in the structure and environment of cancerous tumors. Most women with ovarian cancer are diagnosed with the most advanced form of the disease. Less than a third of those diagnosed with the disease survive five years later. As...
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Glioblastoma is one of the most treatment-resistant cancers, with those diagnosed surviving for less than two years. In a new study in NPJ Genomic Medicine, researchers at the University of Notre Dame have found that a largely understudied cell could offer new insight into how the aggressive, primary brain cancer...
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University of Notre Dame researchers have discovered another way tumor cells transfer genetic material to other cells in their microenvironment, causing cancer to spread. In their latest study, published in Cell Reports, Crislyn D’Souza-Schorey, the Morris Pollard Professor in the Department of Biological Sciences, and collaborators discovered that DNA “cargo”...
Video
Siyuan Zhang studies how medications already commonly prescribed can be used to target cancer.
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Podcast
The American family has changed dramatically over the past four decades, raising urgent questions about marriage, economic stability, and child well-being.
Article
The humble piety of Notre Dame cobbler Brother Columba inspires a canonization push.
Podcast
Mendoza professor Joe Holt joins Jenna Liberto to talk purpose-driven goals, meaningful work, and redefining success.
Article
Observer founder Robert Sam Anson had a contentious yet strong relationship with ND President Father Hesburgh.
Podcast
Anthropologist Cara Ocobock reveals what extreme cold reveals about our bodies and human resilience, and why hunting a “unicorn” is harder than it looks.